In the rapidly evolving field of cancer research, understanding genetic heterogeneity is crucial for developing effective treatments and overcoming drug resistance. This latest application note, "Shasta WGA: Rapid Profiling of CNVs and SNVs in Cancer," provides an in-depth exploration of how the Shasta™ high-throughput single-cell whole-genome amplification (WGA) technology is revolutionizing the way we analyze cancer genomics.
This comprehensive application note details the workflow and results from profiling copy number variations (CNVs) and single nucleotide variations (SNVs) in various cancer cell lines and primary tumor samples. By leveraging the Shasta WGA kit, researchers can generate high-quality DNA-seq libraries from up to 1,500 single cells in a single run, enabling unprecedented insights into tumor heterogeneity.
Key Highlights:
- Enhanced Throughput: Analyze up to 1,500 single cells per run, significantly increasing your research capacity.
- Uniform Coverage: Achieve consistent and reliable results without GC content bias, ensuring high-quality data for your analyses.
- Comprehensive Insights: Identify crucial amplifications and deletions, as well as somatic variations in distinct tumor subpopulations.
- Practical Applications: Utilize findings to inform drug resistance studies and improve therapeutic strategies in oncology.
Don’t miss the opportunity to elevate your research and clinical practice. Download your application note today to gain valuable insights into the Shasta WGA technology and its applications in cancer genomics.
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